Mapping protein post-translational modifications with mass spectrometry

Mapping protein post-translational modifications with mass spectrometry
Post-translational modifications of proteins control many biological processes, and
examining their diversity is critical for understanding mechanisms of cell regulation. Mass
spectrometry is a fundamental tool for detecting and mapping covalent modifications
and quantifying their changes. Modern approaches have made large-scale experiments
possible, screening complex mixtures of proteins for alterations in chemical modifications.
By profiling protein chemistries, biologists can gain deeper insight into biological control.
The aim of this review is introduce biologists to current strategies in mass spectrometry–
based proteomics that are used to characterize protein post-translational modifications,
noting strengths and shortcomings of various approaches.

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清斯濯缨

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cout11

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baal

啥也不说了，感谢一起下吧和楼主的分享哇！

tsanghotung2

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yuanyuan

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猫不咬狗

额，為神馬現在才發現一起下吧的資源啊~@_@